PhD in Neurodegeneration NOMAD

About the LCSB

The University of Luxembourg is an international research university with a distinctly multilingual and interdisciplinary character.

The Luxembourg Centre for Systems Biomedicine (LCSB) is an interdisciplinary research centre of the University of Luxembourg.
We conduct fundamental and translational research in the field of Systems Biology and Biomedicine - in the lab, in the clinic and in silico. We focus on neurodegenerative processes and are especially interested in Alzheimer's and Parkinson's disease and their contributing factors. The LCSB recruits talented scientists from various disciplines: computer scientists, mathematicians, biologists, chemists, engineers, physicists and clinicians from more than 50 countries currently work at the LCSB. We excel because we are truly interdisciplinary, and together we contribute to science and society.

Your role

The Luxembourg Centre for Systems Biomedicine (LCSB) at the University of Luxembourg is looking for an ambitious and dynamic Doctoral Researcher to contribute to the project "Molecular and Cellular Alterations of Noradrenaline-Modulated Memory Circuits in Alzheimer's Disease" (NomAD).

The NomAD project, funded by the Fondation du Pélican de Mie et Pierre Hippert-Faber under the aegis of the Fondation de Luxembourg, is a collaborative effort with leading national and international institutions, including the Laboratoire National de Santé (LNS) in Luxembourg and the Institut de la Mémoire et de la Maladie d'Alzheimer at La Pitié-Salpêtrière Hospital in Paris, France.

As a key member of this project, you will investigate how disruptions in the noradrenergic system affect the vulnerability of memory-associated brain regions in Alzheimer's disease (AD). Your work will include both in vivo and in vitro models, as well as advanced neuropathological analyses of human post-mortem AD brain samples and you will help to uncover cellular signatures that could explain memory decline in AD patients.

Your profile

• A Master's degree (or equivalent) in biology, neuroscience, biomedicine, immunology, or a closely related scientific discipline
• Interest in neurodegeneration and experience with relevant techniques (e.g., cell culture, molecular biology, histology) is considered advantageous
• Previous experience working with mouse models or human induced pluripotent stem cells (iPSC) would be beneficial but is not mandatory
• Strong motivation to conduct impactful research and a willingness to learn new techniques
• An ability to work independently as well as within a collaborative, interdisciplinary research environment
• Excellent organisational and communication skills
• Proficiency in English (written and spoken); knowledge of French or German is a plus but not mandatory

We offer

• Multilingual and international character. Modern institution with a personal atmosphere. Staff coming from 90 countries. Member of the "University of the Greater Region" (UniGR)
• A modern and dynamic university. High-quality equipment. Close ties to the business world and to the Luxembourg labour market. A unique urban site with excellent infrastructure
• A partner for society and industry. Cooperation with European institutions, innovative companies, the Financial Centre and with numerous non-academic partners such as ministries, local governments, associations, NGOs …

How to apply

Applications should include:

• Curriculum Vitae
• Cover letter

Early application is highly encouraged, as the applications will be processed upon reception. Please apply ONLINE formally through the HR system. Applications by Email will not be considered.

All qualified individuals are encouraged to apply. In line with our values, the University of Luxembourg promotes an inclusive culture. We encourage applications from individuals of all backgrounds and are dedicated to upholding equality and respect for our employees and students.

General information:

• Contract Type: Fixed Term Contract 36 Month
• Work Hours: Full Time 40.0 Hours per Week
• Location: Campus Belval
• Internal Title: Doctoral Researcher
• Job Reference: UOL06909

The yearly gross salary for every PhD at the UL is EUR 40952 (full time).